Adaptations to a high fat diet which increase exercise endurance in male rats

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Low-carbohydrate diet -- Physiological effect, Fat, Energy metab
Statementby Wayne C. Miller.
The Physical Object
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Paginationiv, 57 leaves.
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Open LibraryOL13596624M
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Adaptations to a high-fat diet that increase exercise endurance in male rats. Miller WC, Bryce GR, Conlee RK. Eighty-seven male Sprague-Dawley rats ( g) were randomly assigned to one of two experimental groups.

The first group consumed a diet high in fat and low in carbohydrate (LCD), whereas the second group ate a normal diet (ND).Cited by: These data indicate that rats exposed to a high-fat diet are capable of prolonged intense exercise in spite of limited glycogen stores. This improved capacity for exercise appears to be partially the result of muscular adaptations to the diet, which apparently increase the ability to.

– Adaptations to a high-fat diet that increase exercise endurance in male rats Rats were randomly put on either a LCHF diet or a normal diet, after a week the LCHF rats endurance to exhaustion was ~8% longer, and the gap increased to ~33% after five weeks.

These data indicate that rats exposed to a high-fat diet are capable of prolonged intense exercise in spite of limited glycogen stores. This improved capacity for exercise appears to be partially.

Glycogen Repletion and Exercise Endurance in Rats Adapted to a High Fat Diet Robert K. Conlee, Roger L. Hammer, William W. Winder, Mark L. Bracken, Arnold G. Nelson, and David W. Barnett It is well accepted that exercise endurance is directly related to the amount of carbohydrate stored in muscle and that a low carbohydrate diet reduces glycogen storage and exercise by: Ingestion of a high-fat diet for as little as days results in a significant increase in fat oxidation and a decrease in muscle glycogen utilisation during exercise.

In this review, the putative mechanisms underlying the effect of high-fat feeding on altered substrate metabolism during exercise are discussed, including mitochondrial adaptations, such as changes in the enzymes involved in Cited by: 1. J Appl Physio, 6. Coulee RK; Hammer RL, Winder WW, et al: Glycogen repletion and exercise endurance in rats adapted to a high fat diet.

Metabolism7. Miller WC, Bryce GR, Coulee RK: Adaptations to a HFD that increase exercise endurance in male rats. J Appl Physio, by: Sixteen endurance-trained cyclists were assigned randomly to a control (CON) group, who consumed their habitual diet (30% ± 8% mJ fat), or a HFD group, who consumed a high-fat isocaloric diet (69% ± 1% mJ fat).

At 5-day intervals, the subjects underwent an. Metabolic adaptations to a high-fat diet in endurance cyclists. Goedecke JH(1), Christie C, Wilson G, Dennis SC, Noakes TD, Hopkins WG, Lambert EV. Author information: (1)Medical Research Council/University of Capetown Bioenergetics of Exercise Research Unit, University of Cape Town Medical School, Newlands, South by: Get this from a library.

Adaptations to a high fat diet which increase exercise endurance in male rats. [Wayne C Miller]. Subjects that adhered to a low-carbohydrate high-fat diet were significantly higher, exhibiting a potential performance enhancement in endurance capacity.

However, as the authors concluded in this paper, the circulating IL-6 might be harmful inflammatory cytokines and may cause side effects. This might be a limitation of the human study, and a well-designed in vivo or in vitro Cited by: 5. This project has determined cardiac function following endurance exercise for 6 (n = 30) or 12 (n = 25) weeks in male Wistar rats (8 weeks old).

The exercise protocol was 30 min/day at km/h for 5 days/week with an endurance test on the 6th day by running at km/h until by: Metabolic Adaptations to a High-Fat Diet in Endurance Cyclists Julia H.

Goedecke, Candice Christie, Gary Wilson, Steven C. Dennis, "timothy D.

Details Adaptations to a high fat diet which increase exercise endurance in male rats FB2

Noakes, William G. Hopkins, and Estelle V. Lambert. Effects of a high-fat diet and high-carbohydrate diet (CHO) on endurance capacity in trained rats. The bars represent the number of rats that could maintain the same running pace.

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Several studies reported that rats fed a high-fat diet are capable of intense exercise despite a limited muscle glycogen stores [4,6, 8]. In the present study, we did not find differences in. These studies investigated the effects of 2 weeks of either a high-fat (HIGH-FAT: 70% fat, 7% CHO) or a high-carbohydrate (HIGH-CHO: 74% CHO, 12% fat) diet on exercise performance in trained cyclists (n = 5) during consecutive periods of cycle exercise including a Wingate test of muscle power, cycle exercise to exhaustion at 85% of peak power output [90% maximal oxygen uptake (VO2max), high-intensity Cited by: ().

A short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscle. A simple method for the isolation and purification of total lipides from animal tissues. Adaptations to a high-fat diet that increase exercise endurance in male rats.

These studies investigated the effects of 2 weeks of either a high-fat (HIGH-FAT: 70% fat, 7% CHO) or a high-carbohydrate (HIGH-CHO: 74% CHO, 12% fat) diet on exercise performance in trained cyclists (n = 5) during consecutive periods of cycle exercise including a Wingate test of muscle power, cycle exercise to exhaustion at 85% of peak power output [90% maximal oxygen uptake ( Cited by:   Certain conditions, such as several weeks of high-fat diet, disrupt endoplasmic reticulum (ER) homeostasis and activate an adaptive pathway referred as the unfolded protein response.

When the unfolded protein response fails, the result is the development of inflammation and insulin resistance. These two pathological states are known to be improved by regular exercise training but the Cited by:   Food Fight: High Carb or High Fat Diet For Endurance Athletes.

Description Adaptations to a high fat diet which increase exercise endurance in male rats FB2

There is a lot of debate about “training low”, low carb diets, Paleo diets, Atkins diets, fasted training, keto diets, etc. and the more traditional high carbohydrate approach.

Miller WC, Bryce GR, Conlee RK () Adaptations to a high-fat diet that increase exercise endurance in male rats. J Appl Physiol –83 Google Scholar Morgan TE, Cobb LA, Short FA, Ross R, Gunn DR () Effects of long-term exercise on human muscle by: High-fat diets can result in increased fat oxidation after 5 days on a high-fat diet which is only partly explained by substrate availab-ility.

Adaptations at the muscular level that result in changes in substrate utilization in response to a diet may also occur after 5 days. However, high-fat diets. How does the body adapt to a high-fat diet. By increasing the supply of fat and the capacity for fat oxidation in the muscle, thus increasing fat oxidation during exercise.

But this usually occurs at the expense of a reduction in muscle glycogen stores, thus negating any beneficial effects.

Experimental design of the study. 40 male Sprague-Dawley rats were fed a high-fat diet ad libitum for 4 weeks; then animals were divided into 4 Cited by: 5.

High in fat and sugar obese mice exhibit a down regulation of pro-apoptotic genes when compared to lean mice (Ghosh et al., ).This suggests that the molecular adaptation to excess lipid overload by HFS suppresses pro-apoptotic genes which is critical in preventing lipo-apoptosis from occurring in skeletal muscle (Ghosh et al., ).Evidence suggests that in addition to apoptosis, HFS or Cited by: On the other hand, high fat diet intervention is not popular, although it has been reported that a high fat diet induces an increase in mitochondrial biogenesis in skeletal muscle and enhances endurance performance in animal : Kazuhiko Higashida, Mitsuru Higuchi.

Fat utilization: The current science says the absolute maximum amount of fat an athlete can burn is upwards of grams/minute with most highly trained athletes falling into the grams/minute range (Venables ; “Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study”), grams/minute.

In contrast, we found that feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria.

This adaptation appears to be mediated by activation of peroxisome proliferator-activated receptor (PPAR)δ by fatty acids, which results in Cited by: The major metabolic consequences of the adaptations of muscle to endurance exercise are a slower utilization of muscle glycogen and blood glucose, a greater reliance on fat oxidation, and less lactate production during exercise of a given by:   The effects of short-term high fat diets on physiology are elusive and the molecular changes following fat overconsumption remain largely unknown.

In this study, we aimed to evaluate exercise capacity in mice fed with a high fat diet (HFD) for 3 days and investigate the molecular mechanisms in the early response to high-fat feeding.

Exercise capacity was assessed by weight Cited by: 4. A ketogenic diet (KD) could induce nutritional ketosis. Over time, the body will acclimate to use ketone bodies as a primary fuel to achieve keto-adaptation.

Keto-adaptation may provide a consistent and fast energy supply, thus improving exercise performance and capacity. With its anti-inflammatory and anti-oxidative properties, a KD may contribute to muscle health, thus preventing exercise Cited by: 5.Molecular Basis of Rat Skeletal Muscle Phenotype Adaptation in Response to Endurance Exercise and High-Fat Diet To determine the adaptive cha To determine the adaptive changes of rat skeletal muscle phenotype in response to endurance exercise and high fat diet, and further study the mechanism.

40 male SD rats(∼g)were randomized into Control group(CG), exercise group(EG), high fat diet.Obesity, which is caused by energy imbalance and physical inactivity, is strongly associated with increased morbidity and mortality [].Rats that receive a high-fat diet (HFD) are suitable animals for obesity-related studies because they are generally sedentary, and the intensity and duration of their exercise can easily be regulated using treadmill machines [2, 3, 4, 5].Cited by: